5 Natural Antihistamines

If you struggle with seasonal allergies, you’re probably too familiar with all of the symptoms– sneezing, itchy eyes, and a scratchy throat.

Histamine is a protein that triggers allergy symptoms, such as sneezing, itchy eyes, and a scratchy throat. Antihistamines are substances that block histamine activity in the body.

While there are many over-the-counter (OTC) and prescription antihistamine medications, you may want to consider looking to natural aides as well. These food and plant extracts may similarly block the effects of histamine and help to relieve your symptoms:


Vitamin C

Not only does Vitamin C boost the immune system, it is also a powerful antioxidant and anti-inflammatory. Studies show it may act as a treatment for allergies and reduce symptoms.



Butterbur has often been used to treat migraines and allergic rhinitis (hayfever). According to the National Center for Complementary and Integrative Health (NCCIH), butterbur may have antihistamine effects.

While most people tolerate butterbur just fine, it may cause side effects such as:

  • breathing difficulties
  • diarrhea
  • drowsiness
  • fatigue
  • headache
  • itchy eyes



Bromelain is an enzyme found in the core and juice of pineapples and is often used to treat swelling and inflammation, especially of the sinuses.

In some people, bromelain may cause side effects such as:

  • changes in menstruation
  • digestive upset
  • increased heart rate

Those allergic to pineapple should avoid bromelain.



Probiotics are microorganisms that might offer health benefits, such as boosted immune system, by providing a healthful balance of gut bacteria. This boost can help protect against allergies.

The NCCIH say that the evidence for probiotics is mixed and that some probiotics may help while others may not.



Quercetin is an antioxidant found naturally in onions, apples, and other produce that can have anti-allergic and antihistamine properties.